2020 Volume 15 Issue 3
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Zhu Songmei, Dong Yuying, Sha Zhixin, Fang Zheng, Zou Xuejun. Effect of Macrolide Antibiotics on the Urease Activity and Photobacterium phosphoreum[J]. Asian Journal of Ecotoxicology, 2020, 15(3): 116-122. doi: 10.7524/AJE.1673-5897.20200510001
Citation: Zhu Songmei, Dong Yuying, Sha Zhixin, Fang Zheng, Zou Xuejun. Effect of Macrolide Antibiotics on the Urease Activity and Photobacterium phosphoreum[J]. Asian Journal of Ecotoxicology, 2020, 15(3): 116-122. doi: 10.7524/AJE.1673-5897.20200510001
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Effect of Macrolide Antibiotics on the Urease Activity and Photobacterium phosphoreum

  • College of Environment & Resources, Dalian Minzu University, Dalian 116605, China

  • Received Date: 10/05/2020
    Fund Project:
  • The effects of emerging organic contaminants (EOCs) on processes of biological metabolism and performance of ecological engineering have been drawn close concern. Regulating stability of the sludge biochemical process is the key to ensure the quality of the effluent in municipal wastewater treatment plant. The single toxicity effects of azithromycin, erythromycin, roxithromycin, and acetylspiramycin on sludge urease and Photobacterium phosphoreum were analyzed. Different degrees of luminous inhibition by four antibiotics to Photobacterium phosphoreum were observed, the EC50 were 30.05×10-5, 71.70×10-5, 108.6×10-5 and 63.44×10-5 mol·L-1, respectively. The effects on sludge urease showed different stress responses, including hormesis and drug resistance, under different concentration gradients of four antibiotics. In general, consistent decreasing tendency of toxicity were obtained as azithromycin > acetylspiramycin > erythromycin > roxithromycin to urease and Photobacterium phosphoreum. This study could provide basic data for monitoring stressed effect of aquatic ecosystems, evaluating the environmental risks of EOCs, and early warning the disturbances in wastewater treatment processes as well.
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Effect of Macrolide Antibiotics on the Urease Activity and Photobacterium phosphoreum

  • Received Date: 10/05/2020
Fund Project:

Abstract: The effects of emerging organic contaminants (EOCs) on processes of biological metabolism and performance of ecological engineering have been drawn close concern. Regulating stability of the sludge biochemical process is the key to ensure the quality of the effluent in municipal wastewater treatment plant. The single toxicity effects of azithromycin, erythromycin, roxithromycin, and acetylspiramycin on sludge urease and Photobacterium phosphoreum were analyzed. Different degrees of luminous inhibition by four antibiotics to Photobacterium phosphoreum were observed, the EC50 were 30.05×10-5, 71.70×10-5, 108.6×10-5 and 63.44×10-5 mol·L-1, respectively. The effects on sludge urease showed different stress responses, including hormesis and drug resistance, under different concentration gradients of four antibiotics. In general, consistent decreasing tendency of toxicity were obtained as azithromycin > acetylspiramycin > erythromycin > roxithromycin to urease and Photobacterium phosphoreum. This study could provide basic data for monitoring stressed effect of aquatic ecosystems, evaluating the environmental risks of EOCs, and early warning the disturbances in wastewater treatment processes as well.

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