个人护理品中常见抗菌剂的环境分布及毒理学研究进展
Research Progress on Environmental Distribution and Toxicology of Commonly Used Antibacterial Agents in Personal Care Products
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摘要: 个人护理品(PCPs)是人们生活中必不可少的一类日用品，包括洗手液、洗衣液及家用消毒剂等。在抗菌消毒类PCPs中添加的主要抗菌成分有三氯生(TCS)、对氯间二甲苯酚(PCMX)、氯己定(CHX)及季铵化合物(QACs)，近年来这些物质作为新兴污染物在环境及人体中被频繁检出，具有潜在的环境和健康风险。本文系统归纳总结了TCS、PCMX、CHX及QACs的抗菌机制和应用、环境中的检出和归趋，以及毒性效应和健康风险，对深入研究PCPs中常用抗菌剂的毒性效应机制和评估健康风险具有重要参考价值。Abstract: Personal care products (PCPs) are a class of daily necessities in the life of people, including hand sanitizers, laundry detergents, and household disinfectants. The main antibacterial components incorporated into PCPs include triclosan (TCS), p-chloro-m-xylenol (PCMX), chlorhexidine (CHX), and quaternary ammonium compounds (QACs). These antibacterial agents represent emerging pollutants that have been frequently detected in both the environment and human bodies in recent years, thereby posing potential environmental and health risks. This review focuses on the antibacterial mechanisms, applications, detection and fate in the environment, toxic effects, and health risks of these four commonly used antibacterial agents, which provides a reference for further investigating the mechanisms underlying the toxic effects of antimicrobial agents in PCPs and assessing associated health risks.
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Key words:
- TCS /
- PCMX /
- CHX /
- QACs /
- environment detection /
- biological toxicity /
- health risk
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