大环内酯类抗生素对发光菌和脲酶活性影响分析

朱松梅, 董玉瑛, 沙志新, 方政, 邹学军. 大环内酯类抗生素对发光菌和脲酶活性影响分析[J]. 生态毒理学报, 2020, 15(3): 116-122. doi: 10.7524/AJE.1673-5897.20200510001
引用本文: 朱松梅, 董玉瑛, 沙志新, 方政, 邹学军. 大环内酯类抗生素对发光菌和脲酶活性影响分析[J]. 生态毒理学报, 2020, 15(3): 116-122. doi: 10.7524/AJE.1673-5897.20200510001
Zhu Songmei, Dong Yuying, Sha Zhixin, Fang Zheng, Zou Xuejun. Effect of Macrolide Antibiotics on the Urease Activity and Photobacterium phosphoreum[J]. Asian Journal of Ecotoxicology, 2020, 15(3): 116-122. doi: 10.7524/AJE.1673-5897.20200510001
Citation: Zhu Songmei, Dong Yuying, Sha Zhixin, Fang Zheng, Zou Xuejun. Effect of Macrolide Antibiotics on the Urease Activity and Photobacterium phosphoreum[J]. Asian Journal of Ecotoxicology, 2020, 15(3): 116-122. doi: 10.7524/AJE.1673-5897.20200510001

大环内酯类抗生素对发光菌和脲酶活性影响分析

    作者简介: 朱松梅(1995-),女,硕士研究生,研究方向为化学品风险分析和评价,E-mail:1330505737@qq.com
  • 基金项目:

    辽宁省自然科学基金资助项目(20180550107);2020大连民族大学服务国家战略专项

  • 中图分类号: X171.5

Effect of Macrolide Antibiotics on the Urease Activity and Photobacterium phosphoreum

  • Fund Project:
  • 摘要: 新型有机污染物(emerging organic contaminants,EOCs)对生物代谢和生态工程效能的影响受到密切关注。调控污泥生化过程稳定是确保污水处理厂出水水质的关键。为探究EOCs胁迫下污泥脲酶和海洋发光菌的应激效应,分析了阿奇霉素、红霉素、罗红霉素和乙酰螺旋霉素对脲酶和发光菌的毒性作用。结果表明,4种抗生素对发光细菌均呈现出不同程度的抑制作用,其EC50分别为30.05×10-5、71.70×10-5、108.6×10-5和63.44×10-5 mol·L-1;而在不同浓度梯度抗生素的胁迫下,脲酶呈现不同的应激反应,包括毒物兴奋效应和耐药性。抗生素对脲酶和发光菌呈现一致的毒性递减现象:阿奇霉素 > 乙酰螺旋霉素 > 红霉素 > 罗红霉素。研究结果为监控水生生态系统提供了基础数据,为评价EOCs的环境风险和预警污水处理工艺扰动性风险提供参考。
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  • 收稿日期:  2020-05-10
朱松梅, 董玉瑛, 沙志新, 方政, 邹学军. 大环内酯类抗生素对发光菌和脲酶活性影响分析[J]. 生态毒理学报, 2020, 15(3): 116-122. doi: 10.7524/AJE.1673-5897.20200510001
引用本文: 朱松梅, 董玉瑛, 沙志新, 方政, 邹学军. 大环内酯类抗生素对发光菌和脲酶活性影响分析[J]. 生态毒理学报, 2020, 15(3): 116-122. doi: 10.7524/AJE.1673-5897.20200510001
Zhu Songmei, Dong Yuying, Sha Zhixin, Fang Zheng, Zou Xuejun. Effect of Macrolide Antibiotics on the Urease Activity and Photobacterium phosphoreum[J]. Asian Journal of Ecotoxicology, 2020, 15(3): 116-122. doi: 10.7524/AJE.1673-5897.20200510001
Citation: Zhu Songmei, Dong Yuying, Sha Zhixin, Fang Zheng, Zou Xuejun. Effect of Macrolide Antibiotics on the Urease Activity and Photobacterium phosphoreum[J]. Asian Journal of Ecotoxicology, 2020, 15(3): 116-122. doi: 10.7524/AJE.1673-5897.20200510001

大环内酯类抗生素对发光菌和脲酶活性影响分析

    作者简介: 朱松梅(1995-),女,硕士研究生,研究方向为化学品风险分析和评价,E-mail:1330505737@qq.com
  • 大连民族大学环境与资源学院, 大连 116605
基金项目:

辽宁省自然科学基金资助项目(20180550107);2020大连民族大学服务国家战略专项

摘要: 新型有机污染物(emerging organic contaminants,EOCs)对生物代谢和生态工程效能的影响受到密切关注。调控污泥生化过程稳定是确保污水处理厂出水水质的关键。为探究EOCs胁迫下污泥脲酶和海洋发光菌的应激效应,分析了阿奇霉素、红霉素、罗红霉素和乙酰螺旋霉素对脲酶和发光菌的毒性作用。结果表明,4种抗生素对发光细菌均呈现出不同程度的抑制作用,其EC50分别为30.05×10-5、71.70×10-5、108.6×10-5和63.44×10-5 mol·L-1;而在不同浓度梯度抗生素的胁迫下,脲酶呈现不同的应激反应,包括毒物兴奋效应和耐药性。抗生素对脲酶和发光菌呈现一致的毒性递减现象:阿奇霉素 > 乙酰螺旋霉素 > 红霉素 > 罗红霉素。研究结果为监控水生生态系统提供了基础数据,为评价EOCs的环境风险和预警污水处理工艺扰动性风险提供参考。

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