[1] BORRELLE S B, RINGMA J, LAW K L, et al. Predicted growth in plastic waste exceeds efforts to mitigate plastic pollution [J]. Science, 2020, 369(6510): 1515-1518. doi: 10.1126/science.aba3656
[2] REDONDO-HASSELERHARM P E, FALAHUDIN D, PEETERS E T H M, et al. Microplastic effect thresholds for freshwater benthic macroinvertebrates [J]. Environmental Science & Technology, 2018, 52(4): 2278-2286.
[3] KIRAN B R, KOPPERI H, VENKATA MOHAN S. Micro/nano-plastics occurrence, identification, risk analysis and mitigation: Challenges and perspectives [J]. Re/Views in Environmental Science and Bio/Technology, 2022: 27;2735.
[4] GEYER R, JAMBECK J R, LAW K L. Production, use, and fate of all plastics ever made [J]. Science Advances, 2017, 3(7): e1700782. doi: 10.1126/sciadv.1700782
[5] YANG D Q, SHI H H, LI L, et al. Microplastic pollution in table salts from China [J]. Environmental Science & Technology, 2015, 49(22): 13622-13627.
[6] GALLOWAY T S, COLE M, LEWIS C. Interactions of microplastic debris throughout the marine ecosystem [J]. Nature Ecology & Evolution, 2017, 1: 116.
[7] UNITED NATIONS ENVIRONMENT PROGRAMME. UNEP year book: Emerging issues in our global environment [R]. Nairobi, Kenya, 2014.
[8] ZHU K C, JIA H Z, ZHAO S, et al. Formation of environmentally persistent free radicals on microplastics under light irradiation [J]. Environmental Science & Technology, 2019, 53(14): 8177-8186.
[9] LU L, WAN Z Q, LUO T, et al. Polystyrene microplastics induce gut microbiota dysbiosis and hepatic lipid metabolism disorder in mice [J]. Science of the Total Environment, 2018, 631/632: 449-458. doi: 10.1016/j.scitotenv.2018.03.051
[10] LUO T, WANG C Y, PAN Z H, et al. Maternal polystyrene microplastic exposure during gestation and lactation altered metabolic homeostasis in the dams and their F1 and F2 offspring [J]. Environmental Science & Technology, 2019, 53(18): 10978-10992.
[11] QIAO R X, SHENG C, LU Y F, et al. Microplastics induce intestinal inflammation, oxidative stress, and disorders of metabolome and microbiome in zebrafish [J]. Science of the Total Environment, 2019, 662: 246-253. doi: 10.1016/j.scitotenv.2019.01.245
[12] LÖNNSTEDT O M, EKLÖV P. Environmentally relevant concentrations of microplastic particles influence larval fish ecology [J]. Science, 2016, 352(6290): 1213-1216. doi: 10.1126/science.aad8828
[13] ZHANG Y L, GAO T G, KANG S C, et al. Importance of atmospheric transport for microplastics deposited in remote areas [J]. Environmental Pollution, 2019, 254: 112953. doi: 10.1016/j.envpol.2019.07.121
[14] PRATA J C. Airborne microplastics: Consequences to human health? [J]. Environmental Pollution, 2018, 234: 115-126. doi: 10.1016/j.envpol.2017.11.043
[15] AMATO-LOURENÇO L F, CARVALHO-OLIVEIRA R, JÚNIOR Jr, et al. Presence of airborne microplastics in human lung tissue [J]. Journal of Hazardous Materials, 2021, 416: 126124. doi: 10.1016/j.jhazmat.2021.126124
[16] ZHU X, HUANG W, FANG M Z, et al. Airborne microplastic concentrations in five megacities of northern and southeast China [J]. Environmental Science & Technology, 2021, 55(19): 12871-12881.
[17] CAI L Q, WANG J D, PENG J P, et al. Characteristic of microplastics in the atmospheric fallout from Dongguan City, China: Preliminary research and first evidence [J]. Environmental Science and Pollution Research International, 2017, 24(32): 24928-24935. doi: 10.1007/s11356-017-0116-x
[18] DRIS R, GASPERI J, ROCHER V, et al. Microplastic contamination in an urban area: A case study in Greater Paris [J]. Environmental Chemistry, 2015, 12(5): 592. doi: 10.1071/EN14167
[19] DRIS R, GASPERI J, SAAD M, et al. Synthetic fibers in atmospheric fallout: A source of microplastics in the environment? [J]. Marine Pollution Bulletin, 2016, 104(1/2): 290-293.
[20] COX K D, COVERNTON G A, DAVIES H L, et al. Human consumption of microplastics [J]. Environmental Science & Technology, 2019, 53(12): 7068-7074.
[21] ALLEN S, ALLEN D, PHOENIX V R, et al. Atmospheric transport and deposition of microplastics in a remote mountain catchment [J]. Nature Geoscience, 2019, 12(5): 339-344. doi: 10.1038/s41561-019-0335-5
[22] FOURNIER S B, D'ERRICO J N, ADLER D S, et al. Nanopolystyrene translocation and fetal deposition after acute lung exposure during late-stage pregnancy [J]. Particle and Fibre Toxicology, 2020, 17(1): 55. doi: 10.1186/s12989-020-00385-9
[23] EVANGELIOU N, GRYTHE H, KLIMONT Z, et al. Atmospheric transport is a major pathway of microplastics to remote regions [J]. Nature Communications, 2020, 11: 3381. doi: 10.1038/s41467-020-17201-9
[24] DERRAIK J G B. The pollution of the marine environment by plastic debris: A review [J]. Marine Pollution Bulletin, 2002, 44(9): 842-852. doi: 10.1016/S0025-326X(02)00220-5
[25] BRDLÍK P, BORŮVKA M, BĚHÁLEK L, et al. Biodegradation of poly(lactic acid) biocomposites under controlled composting conditions and freshwater biotope [J]. Polymers, 2021, 13(4): 594. doi: 10.3390/polym13040594
[26] AKHBARIZADEH R, DOBARADARAN S, AMOUEI TORKMAHALLEH M, et al. Suspended fine particulate matter (PM2.5), microplastics (MPs), and polycyclic aromatic hydrocarbons (PAHs) in air: Their possible relationships and health implications [J]. Environmental Research, 2021, 192: 110339. doi: 10.1016/j.envres.2020.110339
[27] SALVADOR CESA F, TURRA A, BARUQUE-RAMOS J. Synthetic fibers as microplastics in the marine environment: A review from textile perspective with a focus on domestic washings [J]. Science of the Total Environment, 2017, 598: 1116-1129. doi: 10.1016/j.scitotenv.2017.04.172
[28] NAPPER I E, THOMPSON R C. Release of synthetic microplastic plastic fibres from domestic washing machines: Effects of fabric type and washing conditions [J]. Marine Pollution Bulletin, 2016, 112(1/2): 39-45.
[29] WHO. Advice on the use of masks in the community, during home care and in health care settings [EB]. [2020-06-29].
[30] FADARE O O, OKOFFO E D. Covid-19 face masks: A potential source of microplastic fibers in the environment [J]. The Science of the Total Environment, 2020, 737: 140279. doi: 10.1016/j.scitotenv.2020.140279
[31] ENYOH C E, VERLA A W, VERLA E N, et al. Airborne microplastics: A review study on method for analysis, occurrence, movement and risks [J]. Environmental Monitoring and Assessment, 2019, 191(11): 668. doi: 10.1007/s10661-019-7842-0
[32] WRIGHT S L, ULKE J, FONT A, et al. Atmospheric microplastic deposition in an urban environment and an evaluation of transport [J]. Environment International, 2020, 136: 105411. doi: 10.1016/j.envint.2019.105411
[33] ASHTON K, HOLMES L, TURNER A. Association of metals with plastic production pellets in the marine environment [J]. Marine Pollution Bulletin, 2010, 60(11): 2050-2055. doi: 10.1016/j.marpolbul.2010.07.014
[34] HORTON A A, WALTON A, SPURGEON D J, et al. Microplastics in freshwater and terrestrial environments: Evaluating the current understanding to identify the knowledge gaps and future research priorities [J]. Science of the Total Environment, 2017, 586: 127-141. doi: 10.1016/j.scitotenv.2017.01.190
[35] PRIMPKE S, WIRTH M, LORENZ C, et al. Reference database design for the automated analysis of microplastic samples based on Fourier transform infrared (FTIR) spectroscopy [J]. Analytical and Bioanalytical Chemistry, 2018, 410(21): 5131-5141. doi: 10.1007/s00216-018-1156-x
[36] VIANELLO A, JENSEN R L, LIU L, et al. Simulating human exposure to indoor airborne microplastics using a Breathing Thermal Manikin [J]. Scientific Reports, 2019, 9: 8670. doi: 10.1038/s41598-019-45054-w
[37] SU Y, HU X, TANG H, et al. Steam disinfection releases micro(nano)plastics from silicone-rubber baby teats as examined by optical photothermal infrared microspectroscopy [J]. Nature Nanotechnology, 2022, 17(1): 76-85. doi: 10.1038/s41565-021-00998-x
[38] BATOOL I, QADIR A, LEVERMORE J M, et al. Dynamics of airborne microplastics, appraisal and distributional behaviour in atmosphere;a review [J]. Science of the Total Environment, 2022, 806: 150745. doi: 10.1016/j.scitotenv.2021.150745
[39] LABOR USDO: Regulations (Standards - 29 CFR).
[40] ARAUJO J A, NEL A E. Particulate matter and atherosclerosis: Role of particle size, composition and oxidative stress [J]. Particle and Fibre Toxicology, 2009, 6: 24. doi: 10.1186/1743-8977-6-24
[41] WONG B A. Inhalation exposure systems: Design, methods and operation [J]. Toxicologic Pathology, 2007, 35(1): 3-14. doi: 10.1080/01926230601060017
[42] FIORDELISI A, PISCITELLI P, TRIMARCO B, et al. The mechanisms of air pollution and particulate matter in cardiovascular diseases [J]. Heart Failure Reviews, 2017, 22(3): 337-347. doi: 10.1007/s10741-017-9606-7
[43] LEHNER R, WEDER C, PETRI-FINK A, et al. Emergence of nanoplastic in the environment and possible impact on human health [J]. Environmental Science & Technology, 2019, 53(4): 1748-1765.
[44] YAO Y, GLAMOCLIJA M, MURPHY A, et al. Characterization of microplastics in indoor and ambient air in northern New Jersey [J]. Environmental Research, 2022, 207: 112142. doi: 10.1016/j.envres.2021.112142
[45] WARING R H, HARRIS R M, MITCHELL S C. Plastic contamination of the food chain: A threat to human health? [J]. Maturitas, 2018, 115: 64-68. doi: 10.1016/j.maturitas.2018.06.010
[46] PAULY J L, STEGMEIER S J, ALLAART H A, et al. Inhaled cellulosic and plastic fibers found in human lung tissue [J]. Cancer Epidemiology, Biomarkers & Prevention, 1998, 7(5): 419-428.
[47] ZHANG J J, WANG L, KANNAN K. Microplastics in house dust from 12 countries and associated human exposure [J]. Environment International, 2020, 134: 105314. doi: 10.1016/j.envint.2019.105314
[48] LIU K, WANG X H, FANG T, et al. Source and potential risk assessment of suspended atmospheric microplastics in Shanghai [J]. Science of the Total Environment, 2019, 675: 462-471. doi: 10.1016/j.scitotenv.2019.04.110
[49] DRIS R, GASPERI J, MIRANDE C, et al. A first overview of textile fibers, including microplastics, in indoor and outdoor environments [J]. Environmental Pollution, 2017, 221: 453-458. doi: 10.1016/j.envpol.2016.12.013
[50] SONG Y, LI X, DU X. Exposure to nanoparticles is related to pleural effusion, pulmonary fibrosis and granuloma [J]. The European Respiratory Journal, 2009, 34(3): 559-567. doi: 10.1183/09031936.00178308
[51] ATIS S, TUTLUOGLU B, LEVENT E, et al. The respiratory effects of occupational polypropylene flock exposure [J]. The European Respiratory Journal, 2005, 25(1): 110-117. doi: 10.1183/09031936.04.00138403
[52] HESTERBERG T W, MCCONNELL E E, MIILLER W C, et al. Pulmonary toxicity of inhaled polypropylene fibers in rats [J]. Fundamental and Applied Toxicology, 1992, 19(3): 358-366. doi: 10.1016/0272-0590(92)90174-G
[53] VARELA J A, BEXIGA M G, ÅBERG C, et al. Quantifying size-dependent interactions between fluorescently labeled polystyrene nanoparticles and mammalian cells [J]. Journal of Nanobiotechnology, 2012, 10: 39. doi: 10.1186/1477-3155-10-39
[54] DONG C D, CHEN C W, CHEN Y C, et al. Polystyrene microplastic particles: in vitro pulmonary toxicity assessment [J]. Journal of Hazardous Materials, 2020, 385: 121575. doi: 10.1016/j.jhazmat.2019.121575
[55] YANG S, CHENG Y P, CHEN Z Z, et al. In vitro evaluation of nanoplastics using human lung epithelial cells, microarray analysis and co-culture model [J]. Ecotoxicology and Environmental Safety, 2021, 226: 112837. doi: 10.1016/j.ecoenv.2021.112837
[56] LIM D, JEONG J, SONG K S, et al. Inhalation toxicity of polystyrene micro(nano)plastics using modified OECD TG 412 [J]. Chemosphere, 2021, 262: 128330. doi: 10.1016/j.chemosphere.2020.128330
[57] LI L Z, XU Y, LI S X, et al. Molecular modeling of nanoplastic transformations in alveolar fluid and impacts on the lung surfactant film [J]. Journal of Hazardous Materials, 2022, 427: 127872. doi: 10.1016/j.jhazmat.2021.127872
[58] BERNARD K, HECKER L, LUCKHARDT T R, et al. NADPH oxidases in lung health and disease [J]. Antioxidants & Redox Signaling, 2014, 20(17): 2838-2853.
[59] ZHU J, KOVACS L, HAN W H, et al. Reactive oxygen species-dependent calpain activation contributes to airway and pulmonary vascular remodeling in chronic obstructive pulmonary disease [J]. Antioxidants & Redox Signaling, 2019, 31(12): 804-818.
[60] LANGEN R C J, KORN S H, WOUTERS E F M. ROS in the local and systemic pathogenesis of COPD [J]. Free Radical Biology and Medicine, 2003, 35(3): 226-235. doi: 10.1016/S0891-5849(03)00316-2
[61] SHI Q Y, TANG J C, WANG L, et al. Combined cytotoxicity of polystyrene nanoplastics and phthalate esters on human lung epithelial A549 cells and its mechanism [J]. Ecotoxicology and Environmental Safety, 2021, 213: 112041. doi: 10.1016/j.ecoenv.2021.112041
[62] ZUO L, HALLMAN A H, ROBERTS W J, et al. Superoxide release from contracting skeletal muscle in pulmonary TNF-α overexpression mice [J]. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 2014, 306(1): R75-R81. doi: 10.1152/ajpregu.00425.2013
[63] LITHNER D, LARSSON Å, DAVE G. Environmental and health hazard ranking and assessment of plastic polymers based on chemical composition [J]. Science of the Total Environment, 2011, 409(18): 3309-3324. doi: 10.1016/j.scitotenv.2011.04.038
[64] ZHU K C, JIA H Z, SUN Y J, et al. Enhanced cytotoxicity of photoaged phenol-formaldehyde resins microplastics: Combined effects of environmentally persistent free radicals, reactive oxygen species, and conjugated carbonyls [J]. Environment International, 2020, 145: 106137. doi: 10.1016/j.envint.2020.106137
[65] RUENRAROENGSAK P, TETLEY T D. Differential bioreactivity of neutral, cationic and anionic polystyrene nanoparticles with cells from the human alveolar compartment: Robust response of alveolar type 1 epithelial cells [J]. Particle and Fibre Toxicology, 2015, 12: 19. doi: 10.1186/s12989-015-0091-7
[66] KIM Y, JEONG J, LEE S, et al. Identification of adverse outcome pathway related to high-density polyethylene microplastics exposure: Caenorhabditis elegans transcription factor RNAi screening and zebrafish study [J]. Journal of Hazardous Materials, 2020, 388: 121725. doi: 10.1016/j.jhazmat.2019.121725
[67] YANG L, YUAN Y D. Oxidative damage mechanism of PM2.5 and its relationship with respiratory diseases [J]. Clinical Focus, 2016, 31(4): 433-438.
[68] BROWN D M, WILSON M R, MACNEE W, et al. Size-dependent proinflammatory effects of ultrafine polystyrene particles: A role for surface area and oxidative stress in the enhanced activity of ultrafines [J]. Toxicology and Applied Pharmacology, 2001, 175(3): 191-199. doi: 10.1006/taap.2001.9240
[69] XU M K, HALIMU G, ZHANG Q R, et al. Internalization and toxicity: A preliminary study of effects of nanoplastic particles on human lung epithelial cell [J]. Science of the Total Environment, 2019, 694: 133794. doi: 10.1016/j.scitotenv.2019.133794
[70] LI R, QIU X H, XU F F, et al. Macrophage-mediated effects of airborne fine particulate matter (PM 2.5) on hepatocyte insulin resistance in vitro [J]. ACS Omega, 2016, 1(5): 736-743. doi: 10.1021/acsomega.6b00135
[71] AGHASAFARI P, GEORGE U, PIDAPARTI R. A review of inflammatory mechanism in airway diseases [J]. Inflammation Research, 2019, 68(1): 59-74. doi: 10.1007/s00011-018-1191-2
[72] BARNES P J. The cytokine network in chronic obstructive pulmonary disease [J]. American Journal of Respiratory Cell and Molecular Biology, 2009, 41(6): 631-638. doi: 10.1165/rcmb.2009-0220TR
[73] ZENG Y Y, HU W P, ZUO Y H, et al. Altered serum levels of type I collagen turnover indicators accompanied by IL-6 and IL-8 release in stable COPD [J]. International Journal of Chronic Obstructive Pulmonary Disease, 2019, 14: 163-168. doi: 10.2147/COPD.S188139
[74] CHEN X W, LIU J B, WANG Y L, et al. Inflammatory signal pathway induced by PM2.5: A review of recent studies [J]. Journal of Environment and Health, 2019, 36(10): 857-860.
[75] GOODMAN K E, HARE J T, KHAMIS Z I, et al. Exposure of human lung cells to polystyrene microplastics significantly retards cell proliferation and triggers morphological changes [J]. Chemical Research in Toxicology, 2021, 34(4): 1069-1081. doi: 10.1021/acs.chemrestox.0c00486
[76] ZHANG Y, TEKOBO S, TU Y, et al. Permission to enter cell by shape: Nanodisk vs nanosphere [J]. ACS Applied Materials & Interfaces, 2012, 4(8): 4099-4105.
[77] STROH A, ZIMMER C, GUTZEIT C, et al. Iron oxide particles for molecular magnetic resonance imaging cause transient oxidative stress in rat macrophages [J]. Free Radical Biology and Medicine, 2004, 36(8): 976-984. doi: 10.1016/j.freeradbiomed.2004.01.016
[78] BESSON A, DOWDY S F, ROBERTS J M. CDK inhibitors: Cell cycle regulators and beyond [J]. Developmental Cell, 2008, 14(2): 159-169. doi: 10.1016/j.devcel.2008.01.013
[79] PANAGIOTOU E, GOMATOU G, TRONTZAS I P, et al. Cyclin-dependent kinase (CDK) inhibitors in solid tumors: A review of clinical trials [J]. Clinical & Translational Oncology, 2022, 24(2): 161-192.
[80] JOHNSTON H J, SEMMLER-BEHNKE M, BROWN D M, et al. Evaluating the uptake and intracellular fate of polystyrene nanoparticles by primary and hepatocyte cell lines in vitro [J]. Toxicology and Applied Pharmacology, 2010, 242(1): 66-78. doi: 10.1016/j.taap.2009.09.015
[81] BUCCI-SABATTINI V, CASSINELLI C, COELHO P G, et al. Effect of titanium implant surface nanoroughness and calcium phosphate low impregnation on bone cell activity in vitro [J]. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 2010, 109(2): 217-224. doi: 10.1016/j.tripleo.2009.09.007